DAT Quantitative Reasoning Practice Test 2025 – The Complete All-in-One Guide to Exam Success!

During the formation of glomerular filtrate, the process involves the filtration of blood through the glomeruli in the kidneys. In this process, the blood plasma is filtered across the glomerular membrane, which acts as a selective barrier. The components of blood plasma are subjected to filtration based on size and charge.

The reasoning behind the retention of larger proteins relates directly to the structure and function of the glomerular filtration barrier. This barrier contains specialized cells and layers that allow smaller particles, such as water, electrolytes, and small molecules like glucose, to pass through while restricting larger molecules, such as proteins and cellular elements.

Therefore, larger proteins, which have a higher molecular weight than the filtration threshold, are generally retained in the bloodstream and do not enter the filtrate. This selective filtration process helps maintain the essential protein levels in the blood while allowing for the removal of waste products and excess substances.

In contrast, while all cellular elements like blood cells and larger proteins are typically retained, this does not apply to other components filtered through the glomerulus, such as small ions and nutrients. Major nutrients may also be filtered but are predominantly reabsorbed in the renal tubules. Thus, the correct choice emphasizes the mechanism of protein retention